According to the National Trauma Institute, trauma and injury associated stress is the leading cause of death from 1 to 46 years of age. However, trauma is widespread and has no boundary with regard to age. Although the prevalence of different mechanisms of trauma differ between age groups, all mechanisms of trauma can occur in all age groups. Therefore, our MTOP researchers are dedicated to understanding the psychological and biological mechanisms in those who experience trauma and stress, including children, adults, and elderly populations. This cumulative investigation allows a broader picture of how trauma and stress affects people across their lifespan with potential long-term ramifications.