Neurobiology of Trauma and Stress

MTOP researchers are motivated to better understand how and why psychiatric illnesses like posttraumatic stress disorder (PTSD), anxiety, and depression occur in those exposed to trauma and stress. Using state-of-the-art methods, we emphasize a multi-modal systems approach to combine data across self-report, clinical interviews, neuroimaging, hormone and immune system functioning, and the microbiome. Together, this gives us a larger and more definitive picture of how trauma and stress “get under the skin” to produce resounding changes in mind and body functioning. Advances in science help us design well-rounded studies that test the impact of stress across multiple biological systems, while decades of experience working one-on-one with patients inform directions for scientific inquiry.